Alkaline phosphatase (ALP) is particularly concentrated in liver, kidney, bile duct, bone and placenta tissues.
ALP will increase as a result of acidosis, especially when affecting the aforementioned tissues, but also as a result of:
- Normal bone growth.
- Healing of fractures.
- Chemical medications.
Aspartate Transaminase (AST) is present in liver, heart, skeletal, kidney and pancreatic tissues.
Alanine Transaminase (ALT) is present in heart, skeletal and kidney tissues.
Both AST and ALT will increase as a result of inflammation (acidosis) of the liver. Remember to factor in chemical medications, alcohol and tobacco smoking.
Generally, if it’s deterioration of the liver, you will see an increase in all three liver enzymes.